鲲羽生物经过多年研发、创新和沉淀，在科服板块已建立、完善多条技术产品线，包括高分辨单细胞基因原位杂交、空间转录组测序、空间基因组和单细胞图谱等。近期鲲羽生物已助力客户在Cell、Nat Genet、Neuron、Nat Plants、Dev cell、Nat Commun、Sci Adv、Elife 等国际一流期刊发表重要论文多篇，涉及神经科学、遗传学、表观组学、植物学、肿瘤病理等多个学科领域，在技术层面助力科学家解决关键难题，解锁重要科学现象，推动科学领域重大发现。这一系列研究成果在国际杂志的发表标志着鲲羽生物走向国际、服务全球！
鲲羽生物一直秉持真诚、严谨、科学的态度，秉承助力科学探索、普惠百姓健康、崇尚科技创新、立足产业兴国的理念，在技术上不断寻求突破创新，持续为全球科学研究和技术发展贡献全力。公司也在努力为大家提供更好的产品与服务，推动民族生物原始技术创新走向世界、服务全球！
文章详情：
Xiaoqian Liu, Zunpeng Liu, Zeming Wu, Jie Ren et al.,Resurrection of endogenous retroviruses during aging reinforces senescence. Cell.2023.
Yu J, Xiao K, Chen X, Deng L, Zhang L, Li Y, Gao A, Gao J, Wu C, Yang X, Zhou Q, Yang J, Bao C, Jiao J, Cheng S, Guo Z, Xu W, Cao X, Guo Z, Dai J, Hu J, Fu Z, Cao G. Neuron-derived neuropeptide Y fine-tunes the splenic immune responses. Neuron. 2022.Xu Z, Feng Z, Zhao M, Sun Q, Deng L, Jia X, Jiang T, Luo P, Chen W, Tudi A, Yuan J, Li X, Gong H, Luo Q, Li A. Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei. Elife. 2021.Xiao Q, Huang X, Zhang Y, Xu W, Yang Y, Zhang Q, Hu Z, Xing F, Sun Q, Li G, Li X. The landscape of promoter-centred RNA-DNA interactions in rice. Nat Plants. 2022.Liu Z, Ji Q, Ren J, Yan P, Wu Z, Wang S, Sun L, Wang Z, Li J, Sun G, Liang C, Sun R, Zhao G, Wang H, Zhou Q, Belmonte JCI, Qu J, Zhang W, Liu G. Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging. Dev Cell. 2022.Xiao K, Xiong D, Chen G, Yu J, Li Y, Chen K, Zhang L, Xu Y, Xu Q, Huang X, Gao A, Cao K, Yan K, Dai J, Hu X, Ruan Y, Fu Z, Li G, Cao G. RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription. Sci Adv. 2021.Lin D, Hong P, Zhang S, Xu W, Jamal M, Yan K, Lei Y, Li L, Ruan Y, Fu ZF, Li G, Cao G. Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture. Nat Genet. 2018.Yonghao Sun, Liang Dong, Ying Zhang, Da Lin, Weize XuChangxiong Ke, Linqian Han, Guoliang Li, David Jackson, Xingwang Li, Fang Yang. 3D genome architecture coordinates trans and cis regulation of differentially expressed ear and tassel genes in maize. Genome Biology, 2020.Canhui Cao, Ping Hong, Xingyu Huang, Da Lin, Gang Cao, Liming Wang, Bei Feng, Ping Wu, Hui Shen, Qian Xu, Ci Ren, Yifan Meng, Wenhua Zhi, Ruidi Yu, Juncheng Wei, Wencheng Ding, Xun Tian, Qinghua Zhang, Wei Li, Qinglei Gao, Gang Chen, Kezhen Li, Wing- Kin Sung, Zheng Hu, Hui Wang, Guoliang Li, Peng Wu. HPV CCDC106 Integration Alters Local Chromosome Architecture and Hijacks an Enhancer by Remodeling the 3D Genome Structure in Cervical Cancer. Journal of Genetics and Genomics, 2020.Lin D, Xu W, Hong P, Wu C, Zhang Z, Zhang S, Xing L, Yang B, Zhou W, Xiao Q, Wang J, Wang C, He Y, Chen X, Cao X, Man J, Reheman A, Wu X, Hao X, Hu Z, Chen C, Cao Z, Yin R, Fu ZF, Zhou R, Teng Z, Li G, Cao G. Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation. Nat Commun. 2022.鲲羽生物团队拥有20余年基因原位杂交和10年空间组学研发经验，专注于高灵敏度、高检测效率、单细胞精度、多基因的原位杂交技术和原位测序空间组学技术的研发与应用， 自主研发了高特异性、高分辨率新型原位杂交检测技术和空间多组学原位测序技术，提供从单细胞测序到基因原位检测、空间多维组学一站式解决方案及相关临床诊断产品，满足基础科研与临床应用需求。
18202735305
spatialfish@spatialfish.com
深圳光明国家级高新区、江门新会国家级高新区
